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arznei-telegramm®  07/2017

SPOT ON
Profiteering with orphan drugs … 450-fold price increase within seven years

NEW ON THE MARKET
Baricitinib (OLUMIANT) and tofacitinib (XELJANZ) against rheumatoid arthritis

THERAPY FROM A CRITICAL VIEWPOINT
CANVAS trial with canagliflozin (INVOCANA) – second endpoint trial with an SGLT-2 inhibitor
Bioresorbable coronary stents: disappointing results

a-t READERS QUESTIONS AND COMMENTS
Glatiramer acetate generic CLIFT

IN BRIEF
SCORE 2 trial: bevacizumab (AVASTIN) versus aflibercept (EYLEA) in retinal vein occlusion
No benefit of high dose baclofen (LIORESAL, generics) in alcohol-dependent patients
Azithromycin gel against borreliosis?

CURRENT ADR NETWORK REPORT
Genital mycosis with empagliflozin (JARDIANCE)

SIDE EFFECTS
Fatal liver failure with daclizumab (ZINBRYTA)
Cardiovascular side effects with brimonidine (MIRVASO)

e a-t ON THE INTERNET
Osteonecrosis of the external auditory canal with denosumab (PROLIA, XGEVA)